Simulation-based approach provides a very powerful, rich, and versatile paradigm for many disciplines, methodologies, and studies. Already over 170 disciplines, methodologies, and approaches are simulation-based. The article clarifies the essence and power of simulation-based approach. To reach this aim the following is done: First, as a basis, the essence of simulation which consists of experimentation and experience is covered. The historic rise of the experimentation in early 17th century as a basis of scientific method as well as the additional benefits of simulated experiments are covered. The unique advantages of coupling simulation and the working of real systems are explained. Possibilities offered by simulation to gain three types of experience are clarified. A brief history of model-based approach as well as the first discipline for which model-based approach was promoted are explained. Richness and versatility of simulation and benefits of its use are detailed. The power gained by first and higher-order synergies of simulation with several other disciplines such as system theories, systems engineering, computers, software engineering, software agents, and reliability are mentioned. The already achieved shift of paradigm from model-based to simulation-based is strongly endorsed.
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