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  1. No Access手机体育投注平台

    Protocol

    Co-transcriptional Analysis of Self-Cleaving Ribozymes and Their Ligand Dependence

    Self-cleaving ribozymes are RNA molecules that catalyze a site-specific self-scission reaction. Analysis of self-cleavage is a crucial aspect of the biochemical study and understanding of these molecules. Here...

    Luiz F. M. Passalacqua, Andrej Lupták in Ribozymes (2021)

  2. Article

    Open Access

    RNA motif search with data-driven element ordering

    In this paper, we study the problem of RNA motif search in long genomic sequences. This approach uses a combination of sequence and structure constraints to uncover new distant homologs of known functional RNA...

    Ladislav Rampášek, Randi M. Jimenez, Andrej Lupták, Tomáš Vinař in BMC Bioinformatics (2016)

  3. No Access

    手机体育投注平台 Article

    In situ NMR measurement of macromolecule-bound metal ion concentrations

    Many nucleic acids and proteins require divalent metal ions such as Mg2+ and Ca2+ for folding and function. The lipophilic alignment media frequently used as membrane mimetics also bind these divalent metals. Her...

    Natalia Kozlyuk, Suvrajit Sengupta, Andrej Lupták in Journal of Biomolecular NMR (2016)

  4. No Access手机体育投注平台

    Protocol

    Discovery of RNA Motifs Using a Computational Pipeline that Allows Insertions in Paired Regions and Filtering of Candidate Sequences

    手机体育投注平台 The enormous impact of noncoding RNAs on biology and biotechnology has motivated the development of systematic approaches to their discovery and characterization. Here we present a methodology for reliable det...

    Randi M. Jimenez, Ladislav Rampášek, Broňa Brejová, Tomáš Vinař, Andrej Lupták in Ribozymes (2012)

  5. No Access

    手机体育投注平台 Protocol

    Structure-Based Search and In Vitro Analysis of Self-Cleaving Ribozymes

    手机体育投注平台 Detecting functional RNAs is increasingly accomplished through structure-based searches for patterns of conserved secondary structure. With large amounts of new sequencing data becoming available, there is a g...

    Randi M. Jimenez, Andrej Lupták in Ribozymes (2012)