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  1. No Access手机体育投注平台

    Protocol

    Cloning and Detection of Aptamer-Ribozyme Conjugations

    RNA aptamers can be used to target proteins or nucleic acids for therapeutic purposes and are candidates for RNA-mediated gene therapy. Like other small therapeutic RNAs, they can be expressed in cells from DN...

    Ryan P. Goguen, Anne Gatignol, Robert J. Scarborough in Ribozymes (2021)

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    Protocol

    Design and Evaluation of Clinically Relevant SOFA-HDV Ribozymes Targeting HIV RNA

    Nucleic acid therapies targeting HIV replication have the potential to be used in conjunction with or in place of the standard small-molecule therapies. Among the different classes of nucleic acid therapies, s...

    Robert J. Scarborough, Michel V. Lévesque in Therapeutic Applications of Ribozymes and … (2014)

  3. 手机体育投注平台 Article

    Open Access

    Inhibition of HIV-1 expression and replication by SOFA-HDV ribozymes against Tat and Rev mRNA sequences

    手机体育投注平台

    Sébastien Lainé, Robert J Scarborough, Dominique Lévesque in Retrovirology (2009)

  4. 手机体育投注平台 Article

    Open Access

    Characterization of the TRBP domain required for Dicer interaction and function in RNA interference

    手机体育投注平台 Dicer, Ago2 and TRBP are the minimum components of the human RNA-induced silencing complex (RISC). While Dicer and Ago2 are RNases, TRBP is the double-stranded RNA binding protein (dsRBP) that loads small inte...

    Sylvanne M Daniels, Carlos E Melendez-Peña, Robert J Scarborough in BMC Molecular Biology (2009)