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    手机体育投注平台 Protocol

    RNA Editing in Neurological and Neurodegenerative Disorders

    手机体育投注平台 The brain is one of the organs that are preferentially targeted by adenosine-to-inosine (A-to-I) RNA editing, a posttranscriptional modification. This chemical modification affects neuronal development and fun...

    Pedro Henrique Costa Cruz, Yukio Kawahara in RNA Editing (2021)

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    Article

    Adenosine-to-inosine RNA editing in the immune system: friend or foe?

    Our body expresses sensors to detect pathogens through the recognition of expressed molecules, including nucleic acids, lipids, and proteins, while immune tolerance prevents an overreaction with self and the d...

    Taisuke Nakahama, Yukio Kawahara in Cellular and Molecular Life Sciences (2020)

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    Cross-Linking and Immunoprecipitation of Nuclear RNA-Binding Proteins

    The systematic identification of in vivo targets of nuclear RNA-binding proteins (RBPs) is crucial to elucidate the physiological functions of each RBP. However, it has been difficult to distinguish real targe...

    Quan Li, Yuri Uemura, Yukio Kawahara in Nuclear Bodies and Noncoding RNAs (2015)

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    Article

    Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis

    One plausible hypothesis for selective neuronal death in sporadic amyotropic lateral sclerosis (ALS) is excitotoxicity mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors, which are a...

    Shin Kwak, Yukio Kawahara in Journal of Molecular Medicine (2005)